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C-021

CAT: 0013-GTR19172969-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172969-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C-021 dihydrochloride is a potent and selective CCR4 antagonist, inhibiting human and mouse chemotaxis with IC50 values of 140 nM and 39 nM, respectively. It blocks CCL22-induced GTPγS binding (IC50: 18 nM) and is a valuable tool for investigating CCR4-mediated responses in both in vitro and in vivo immunological research models.
CAS Number
864289-85-0
Product Name Alternative
4-​Quinazolinamine, 2-​[1, ​4'-​bipiperidin]​-​1'-​yl-​N-​cycloheptyl-​6, ​7-​dimethoxy-, CCR, CCL22, C 021, C021, C-021, CC chemokine receptor, CCR4, chemotaxis, inhibit, Inhibitor, GTPγS
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.74% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.07 mM) ; DMSO:9 mg/mL (19.25 mM)
Smiles
N (C=1C2=C (N=C (N1) N3CCC (CC3) N4CCCCC4) C=C (OC) C (OC) =C2) C5CCCCCC5
Molecular Formula
C27H41N5O2
Molecular Weight
467.65
Storage Conditions
-20°C
Notes
For research use only.

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