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BW 755C

CAT: 0013-GTR19172907-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172907-03Size:10 mg
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Description
BW 755C is a dual-action small molecule inhibitor that simultaneously blocks both the 5-lipoxygenase (5-LO) and cyclooxygenase (COX) enzymatic pathways. It is widely used in pharmacological research to study eicosanoid biosynthesis and inflammation in both cellular (in vitro) and animal (in vivo) experimental models.
CAS Number
66000-40-6
Product Name Alternative
5-LOX, BW 755C
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience
Purity
96.52% (May vary between batches)
Solubility
Ethanol:20 mg/mL (87.26 mM) ; DMSO:25 mg/mL (109.08 mM)
Smiles
C (F) (F) (F) C=1C=C (C=CC1) N2N=C (N) CC2
Molecular Formula
C10H10F3N3
Molecular Weight
229.2
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine

A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.

CAS Number66000-40-6
PubChem CID47795
IUPAC Name2-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazol-5-amine
Molecular FormulaC10H10F3N3
Molecular Weight229.20
XLogP1.8
Topological Polar Surface Area41.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Heavy Atom Count16
Formal Charge0
Complexity288
SMILES
C1CN(N=C1N)C2=CC=CC(=C2)C(F)(F)F
InChI
InChI=1S/C10H10F3N3/c11-10(12,13)7-2-1-3-8(6-7)16-5-4-9(14)15-16/h1-3,6H,4-5H2,(H2,14,15)
InChIKey
CPXGGWXJNQSFEP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
CAS: 66000-40-6
CID: 47795
Formula: C10H10F3N3
MW: 229.20
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight229.20
XLogP31.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass229.08268182
Monoisotopic Mass229.08268182
Topological Polar Surface Area41.6 Ų
Heavy Atom Count16
Formal Charge0
Complexity288
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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