CBFβ Inhibitor

CAT: 0013-GTR19172871-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19172871-01Size:2 mg

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Description

This small molecule inhibitor is cell-permeable and specifically disrupts the interaction between CBFβ and Runx1. It serves as a valuable research tool for studying Runx complex function in hematopoiesis and leukemia, applicable in both cellular and biochemical assays.

CAS Number

493028-20-9

Product Name Alternative

RNA Synthesis, RNASynthesis, 5-Ethyl-4- (4-methoxy-phenyl) -thiazol-2-ylamine, CBF, CBFβ Inhibitor, CBFb Inhibitor, CBFbeta Inhibitor, DNA Synthesis, DNASynthesis

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Purity

96.50% (May vary between batches)

Solubility

Ethanol:25 mg/mL (106.69 mM) ; DMSO:55 mg/mL (234.72 mM)

Smiles

CCC1=C (N=C (N) S1) C1=CC=C (OC) C=C1

Molecular Formula

C12H14N2OS

Molecular Weight

234.32

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine

CAS Number	493028-20-9
PubChem CID	828523
IUPAC Name	5-ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
Molecular Formula	C12H14N2OS
Molecular Weight	234.32
XLogP	3.1
Topological Polar Surface Area	76.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	16
Formal Charge	0
Complexity	219

SMILES

CCC1=C(N=C(S1)N)C2=CC=C(C=C2)OC

InChI

InChI=1S/C12H14N2OS/c1-3-10-11(14-12(13)16-10)8-4-6-9(15-2)7-5-8/h4-7H,3H2,1-2H3,(H2,13,14)

InChIKey

QHRCVGXBBIRPTE-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 493028-20-9

CID: 828523

Formula: C12H14N2OS

MW: 234.32

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	234.32
XLogP3	3.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	234.08268425
Monoisotopic Mass	234.08268425
Topological Polar Surface Area	76.4 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	219
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

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C3398-5	CBFβ Inhibitor
BUP02120-01	CBFß Inhibitor
562893	CBFÎ² Inhibitor
HY-124137-01	Runx1-CBFβ interaction inhibitor 1
217258	CBF beta-Runx1 Inhibitor II (Ro5-3335)
GS-0008	CBF, EMSA
F48151-0.08ML	CBF Antibody
520989-01	CBF-C
33875-01	CBF β Antibody
520988-01	CBF beta

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Chemical Information

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