Products for Research Use Only

BPR1J-097

CAT: 0013-GTR19172622-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172622-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BPR1J-097 is a potent and selective small molecule inhibitor of FLT-3, demonstrating an IC50 of 11±7 nM against the wild-type kinase and 3 nM against the D835Y mutant. It exhibits significant anti-leukemic activity in cellular assays and has shown promising efficacy in preclinical in vivo models of FLT3-ITD-driven acute myeloid leukemia.
CAS Number
1327167-19-0
Product Name Alternative
Cluster of differentiation antigen 135, CD135, BPR1J 097, BPR1J097, BPR-1J-097, BPR1J-097, Fms like tyrosine kinase 3, FLT3, Inhibitor, inhibit
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.30% (May vary between batches)
Solubility
DMSO:11 mg/mL (21.29 mM)
Smiles
CN1CCN (CC1) c1ccc (cc1) C (=O) Nc1cc ([nH]n1) -c1cccc (NS (=O) (=O) c2ccccc2) c1
Molecular Formula
C27H28N6O3S
Molecular Weight
516.61
Storage Conditions
-20°C
Notes
For research use only.