Nazartinib

CAT: 0013-GTR19172221-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19172221-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Nazartinib (EGF816) is an irreversible, mutant-selective EGFR inhibitor. It potently and selectively targets common activating mutations (L858R, ex19del) and the T790M resistance mutation, showing significant selectivity over wild-type EGFR in biochemical and cellular assays. Its research applications include in vitro mechanistic studies and in vivo models of non-small cell lung cancer (NSCLC) .

CAS Number

1508250-71-2

Product Name Alternative

EGF 816, EGFR, EGF-816, EGF816, EGFR (mutant), Epidermal growth factor receptor, ErbB-1, HER1, Inhibitor, inhibit, Nazartinib, NVS 816, NVS816, NVS-816

Field of Research

Cardiovascular Research, Signal Transduction

Purity

≥95% (May vary between batches)

Solubility

Ethanol:92 mg/mL (185.85 mM) ; DMSO:92 mg/mL (185.85 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CN (C) C\C=C\C (=O) N1CCCC[C@H] (C1) n1c (NC (=O) c2ccnc (C) c2) nc2cccc (Cl) c12

Molecular Formula

C26H31ClN6O2

Molecular Weight

495.02

Storage Conditions

-20°C

Notes

For research use only.

Alternative Products

Catalog	Name
HY-12872-01	Nazartinib
C12979-25mg	Nazartinib (EGF816)
IKC25072-01	Nazartinib mesylate
MBS3840357-01	EGF816 (Nazartinib)
A14416-100	EGF816 (Nazartinib) 100mg
A14416-25	EGF816 (Nazartinib) 25mg
MBS3846171-01	Nazartinib S-enantiomer
A21741-100	Nazartinib mesylate 100mg
A14416-500	EGF816 (Nazartinib) 500mg

Nazartinib

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