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Nazartinib

CAT: 0931-T3506-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T3506-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1508250-71-2
Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
0.9962
Bioactivity
Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
Smiles
CN(C)C\C=C\C(=O)N1CCCC[C@H](C1)n1c(NC(=O)c2ccnc(C)c2)nc2cccc(Cl)c12
Molecular Formula
C26H31ClN6O2
Molecular Weight
495.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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