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PFI-1

CAT: 0013-GTR19172061-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172061-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PFI-1 (PF-6405761) is a potent and selective BET bromodomain inhibitor, exhibiting an IC50 of 0.22 μM against BRD4 in biochemical assays. This cell-permeable compound is a valuable chemical probe for investigating BET protein function in cancer, inflammation, and transcriptional regulation in both cellular and animal models.
CAS Number
1403764-72-6
Product Name Alternative
Apoptosis, Autophagy, BRD2, BRD4, Epigenetic Reader Domain, EpigeneticReaderDomain, Inhibitor, inhibit, PF6405761, PF-6405761, PFI1, PFI-1, PFI 1, PF 6405761
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
97.21% (May vary between batches)
Solubility
DMSO:40 mg/mL (115.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.76 mM)
Smiles
COc1ccccc1S (=O) (=O) Nc1ccc2NC (=O) N (C) Cc2c1
Molecular Formula
C16H17N3O4S
Molecular Weight
347.39
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
HY-16586-01PFI-1
4445/50PFI 1
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A12545-50PFI-1 50mg
A12545-10PFI-1 10mg
A12545-5PFI-1 5mg
C16192-10mM/1mLPFI-1 (PF-6405761)
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