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WZ4002

CAT: 0013-GTR19172043-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172043-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WZ4002 is a potent and selective small molecule inhibitor targeting the EGFR mutants L858R and T790M, with IC50 values of 2 nM and 8 nM, respectively. It is a valuable research tool for studying resistance mechanisms in non-small cell lung cancer and has demonstrated efficacy in both cellular assays and preclinical in vivo models.
CAS Number
1213269-23-8
Product Name Alternative
WZ 4002, WZ4002, WZ-4002, inhibit, EGFR, Epidermal growth factor receptor, EGFR (L858R), EGFR (L858R/T790M), ErbB-1, Inhibitor, HER1
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.51% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:11 mg/mL (22.22 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O (C) C=1C=C (C=CC1NC=2N=C (OC3=CC (NC (C=C) =O) =CC=C3) C (Cl) =CN2) N4CCN (C) CC4
Molecular Formula
C25H27ClN6O3
Molecular Weight
494.97
Storage Conditions
-20°C
Notes
For research use only.

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