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Rupatadine Fumarate

CAT: 0013-GTR19172039-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172039-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rupatadine Fumarate (UR-12592 Fumarate) is a dual antagonist of platelet-activating factor (PAF) and the histamine H1 receptor, exhibiting high potency with respective Ki values of 0.55 μM and 0.1 μM. This small molecule is utilized in research to study allergic inflammation and anaphylaxis, with applications in both in vitro binding assays and in vivo models of allergic response.
CAS Number
182349-12-8
Product Name Alternative
Rupafin, Rupatadine, Rupatadine Fumarate, rhinitis, Rinialer, urticaria, UR 12592, UR12592, UR-12592, Autophagy, Alergoliber, allergic, PAFR, PAF, Inhibitor, inhibit, Histamine Receptor, HistamineReceptor, H1 receptor
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.64% (May vary between batches)
Solubility
Ethanol:11 mg/mL (20.68 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.76 mM) ; DMSO:12 mg/mL (22.56 mM)
Smiles
OC (=O) \C=C\C (O) =O.Cc1cncc (CN2CC\C (CC2) =C2/c3ccc (Cl) cc3CCc3cccnc23) c1
Molecular Formula
C26H26ClN3·C4H4O4
Molecular Weight
532.03
Storage Conditions
-20°C
Notes
For research use only.

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