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VTP50469 fumarate

CAT: 0013-GTR19205013Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19205013Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VTP50469 fumarate is a potent, orally bioavailable small molecule that selectively inhibits the Menin-MLL interaction with picomolar affinity. It demonstrates robust anti-leukemic efficacy in both cellular assays and in vivo models, making it a valuable chemical probe for researching MLL-rearranged leukemias.
CAS Number
2169919-29-1
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
OC (/C=C/C (O) =O) =O.CC (C) N (C (C) C) C (C (C=C (C=C1) F) =C1OC2=CN=CN=C2N (C3) CC3 (CC4) CCN4C[C@@H]5CC[C@H] (CC5) NS (C) (=O) =O) =O.CC (C) N (C (C) C) C (C (C=C (C=C6) F) =C6OC7=CN=CN=C7N (C8) CC8 (CC9) CCN9C[C@@H]%10CC[C@H] (CC%10) NS (C) (=O) =O) =O.OC (/C=C/C (O) =O) =O.OC (/C=C/C (O) =O) =O
Molecular Formula
C76H106F2N12O20S2
Molecular Weight
1609.86
Storage Conditions
-20°C
Notes
For research use only.

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