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EN106

CAT: 0013-GTR19171843-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171843-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EN106 is a covalent, cysteine-targeting small molecule that potently inhibits FEM1B, disrupting its interaction with the reductive stress sensor FNIP1. This tool compound enables the study of the FEM1B-FNIP1 pathway in cellular and in vivo models of redox biology and related diseases.
CAS Number
757192-67-9
Product Name Alternative
EN106, EN-106, EN 106, FEMIB, ZINC3888023, ZINC-3888023, ZINC 3888023
Field of Research
Immunology & Inflammation, Protein Biochemistry, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:200 mg/mL (712.48 mM)
Smiles
ClCC (=O) N (CCC#N) c1ccc2OCCOc2c1
Molecular Formula
C13H13ClN2O3
Molecular Weight
280.71
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-chloro-N-(2-cyanoethyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS Number757192-67-9
PubChem CID5100616
IUPAC Name2-chloro-N-(2-cyanoethyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
Molecular FormulaC13H13ClN2O3
Molecular Weight280.70
XLogP1.3
Topological Polar Surface Area62.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count19
Formal Charge0
Complexity368
SMILES
C1COC2=C(O1)C=CC(=C2)N(CCC#N)C(=O)CCl
InChI
InChI=1S/C13H13ClN2O3/c14-9-13(17)16(5-1-4-15)10-2-3-11-12(8-10)19-7-6-18-11/h2-3,8H,1,5-7,9H2
InChIKey
GLDJSVHDOXCYPT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-chloro-N-(2-cyanoethyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS: 757192-67-9
CID: 5100616
Formula: C13H13ClN2O3
MW: 280.70
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight280.70
XLogP31.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass280.0614700
Monoisotopic Mass280.0614700
Topological Polar Surface Area62.6 Ų
Heavy Atom Count19
Formal Charge0
Complexity368
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T60096-01EN106

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