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Pacritinib

CAT: 0013-GTR19171821-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171821-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pacritinib (SB1518) is a potent and selective small molecule inhibitor targeting JAK2 and FLT3 kinases, with cell-free assay IC50 values of 23 nM and 22 nM, respectively. It is widely used in preclinical research for studying myeloproliferative neoplasms and acute myeloid leukemia, demonstrating activity in both cellular assays and in vivo models.
CAS Number
937272-79-2
Product Name Alternative
Inhibitor, Fms like tyrosine kinase 3, FLT3, FLT3 (D835Y), Janus kinase, JAK3, JAK2 (V617F), JAK, JAK2, inhibit, Pacritinib, Cluster of differentiation antigen 135, CD135, SB 1518, SB1518, SB-1518, TyrosineKinases, Tyrosine Kinases, Tyk2
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
≥95% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.12 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:3.57 mg/mL (7.55 mM)
Smiles
C (CN1CCCC1) Oc1ccc2Nc3nccc (n3) -c3cccc (COC\C=C\COCc1c2) c3
Molecular Formula
C28H32N4O3
Molecular Weight
472.58
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-16379-01Pacritinib
HY-16379B-01Pacritinib (citrate)
HY-16379R-01Pacritinib (Standard)
202571Pacritinib (SB1518)
MBS5806943Pacritinib hydrochloride
CS-O-59407Pacritinib-d8
B2485-1EZSolution™ Pacritinib

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