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GNE0877

CAT: 0013-GTR19171810-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171810-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNE-0877 is a potent and selective small molecule inhibitor of LRRK2 kinase, exhibiting a Ki of 0.7 nM. It is a valuable research tool for investigating LRRK2 biology in cellular models and has been utilized in preclinical in vivo studies relevant to Parkinson's disease research.
CAS Number
1374828-69-9
Product Name Alternative
Small molecule, brain-penetrant, oral, LRRK2, inhibit, liver microsomes, Leucine-rich repeat kinase 2, Inhibitor, GNE 0877, GNE0877, GNE-0877
Field of Research
Cell Biology
Purity
98.01% (May vary between batches)
Solubility
DMSO:45 mg/mL (132.62 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CNc1nc (Nc2cn (nc2C) C (C) (C) C#N) ncc1C (F) (F) F
Molecular Formula
C14H16F3N7
Molecular Weight
339.32
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
B4633-10GNE0877
A13969-500GNE0877 500mg
A13969-100GNE0877 100mg
A13969-50GNE0877 50mg
A13969-25GNE0877 25mg
A13969-10GNE0877 10mg
A13969-5GNE0877 5mg
A13969-2GNE0877 2mg
A13969-1GNE0877 1mg
A13969-10mM-DGNE0877 10mM * 1mL in DMSO

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