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Selinexor

CAT: 0013-GTR19171738-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171738-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selinexor (KPT-330) is an orally bioavailable, selective inhibitor of Exportin 1 (XPO1/CRM1) . It induces cell cycle arrest and apoptosis, demonstrating antitumor activity in preclinical models of multiple myeloma, including both in vitro cell studies and in vivo xenograft experiments.
CAS Number
1393477-72-9
Product Name Alternative
KPT-330
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Inhibitor of the nuclear export receptor CRM1/XPO1
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
Smiles
FC (F) (F) c1cc (cc (c1) C (F) (F) F) -c1ncn (\C=C/C (=O) NNc2cnccn2) n1
Molecular Formula
C17H11F6N7O
Molecular Weight
443.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(Z) -3-[3-[3,5-Bis (trifluoromethyl) phenyl]-1,2,4-triazol-1-yl]-N’-pyrazin-2-ylprop-2-enehydrazide

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