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Firibastat

CAT: 0013-GTR19171564-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171564-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Firibastat (RB150) is an orally active, brain-penetrating prodrug of EC33 and a first-in-class aminopeptidase A (APA) inhibitor (Ki=200 nM) . It selectively blocks the conversion of angiotensin-II to angiotensin-III in the brain, demonstrating antihypertensive effects in rodent models of hypertension and serving as a key research tool for studying the brain renin-angiotensin system.
CAS Number
648927-86-0
Product Name Alternative
QGC 001, QGC001, QGC-001, Inhibitor, inhibit, hypertensive, Firibastat, Aminopeptidase A, Aminopeptidase, angiotensin, brain, blood, RB150, RB-150, RB 150, pressure
Field of Research
Metabolism Research
Purity
99.50% (May vary between batches)
Solubility
H2O:30 mg/mL (81.41 mM)
Smiles
N[C@@H] (CCS (O) (=O) =O) CSSC[C@@H] (N) CCS (O) (=O) =O
Molecular Formula
C8H20N2O6S4
Molecular Weight
368.51
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T28482-01Firibastat
HY-109058R-01Firibastat (Standard)

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