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Firibastat

CAT: 0931-T28482-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T28482-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
648927-86-0
Target
Aminopeptidase
Related Pathways
Metabolism
Purity
0.9988
Bioactivity
Firibastat (RB150) is a glutamyl aminopeptidase antagonist and an orally active brain penetrating prodrug of EC33. It is a first-in-class brain aminopeptidase A (APA) inhibitor with a Ki of 200 nM. Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats[1][2].
Smiles
N[C@@H](CCS(O)(=O)=O)CSSC[C@@H](N)CCS(O)(=O)=O
Molecular Formula
C8H20N2O6S4
Molecular Weight
368.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA7173-25Firibastat
HY-109058R-01Firibastat (Standard)

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