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A83-01

CAT: 0013-GTR19171532-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171532-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A 83-01 is a potent inhibitor of TGF-β type I receptors ALK5, ALK4, and ALK7. It facilitates the generation of induced pluripotent stem cells (iPSCs) from somatic cells and is widely used to support the growth and maintenance of various organoid cultures in vitro.
CAS Number
909910-43-6
Product Name Alternative
A8301, A83-01, A 83 01, A 8301, A 83-01, ALK4, ALK5, ALK5 Inhibitor IV, ALK, ALK7, inhibit, Inhibitor, TGF-β/Smad, TGFβ, TGF-β Receptor, Transforming growth factor beta receptors, TGFbeta, TGF-b/Smad, TGFb, TGF-beta, TGFbeta/Smad, Smad
Field of Research
Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
ALK inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml) .
Smiles
Cc1cccc (n1) -c1nn (cc1-c1ccnc2ccccc12) C (=S) Nc1ccccc1
Molecular Formula
C25H19N5S
Molecular Weight
421.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3- (6-Methyl-2-pyridinyl) -N-phenyl-4- (4-quinolinyl) -1H-pyrazole-1-carbothioamide

Chemical Information

A-83-01

3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)-1H-pyrazole-1-carbothioamide is an organic molecular entity.

CAS Number909910-43-6
PubChem CID16218924
IUPAC Name3-(6-methyl-2-pyridinyl)-N-phenyl-4-quinolin-4-ylpyrazole-1-carbothioamide
Molecular FormulaC25H19N5S
Molecular Weight421.5
XLogP5
Topological Polar Surface Area87.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count31
Formal Charge0
Complexity609
SMILES
CC1=NC(=CC=C1)C2=NN(C=C2C3=CC=NC4=CC=CC=C34)C(=S)NC5=CC=CC=C5
InChI
InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31)
InChIKey
HIJMSZGHKQPPJS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of A-83-01
CAS: 909910-43-6
CID: 16218924
Formula: C25H19N5S
MW: 421.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight421.5
XLogP35
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass421.13611680
Monoisotopic Mass421.13611680
Topological Polar Surface Area87.7 Ų
Heavy Atom Count31
Formal Charge0
Complexity609
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS808125-01A83 01
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1989-1EZSolution™ A83-01, Sterile-Filtered
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PTX25652Anti-Human CD47/MER6 (HMPL-a83)
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