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SGC-707

CAT: 0013-GTR19171481-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171481-01Size:5 mg
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Description
SGC707 is a cell-permeable, allosteric small molecule that potently and selectively inhibits PRMT3. It serves as a valuable chemical probe for investigating PRMT3's role in ribosome biogenesis and cellular differentiation in both in vitro and in vivo research contexts.
CAS Number
1687736-54-4
Product Name Alternative
PRMT3, SGC707, SGC-707, SGC 707, inhibit, Histone Methyltransferase, HistoneMethyltransferase, Inhibitor
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
PRMT3 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 35 mg/ml)
Smiles
O=C (NCC (=O) N1CCCC1) Nc1ccc2cnccc2c1
Molecular Formula
C16H18N4O2
Molecular Weight
298.34
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-Isoquinolin-6-yl-3- (2-oxo-2-pyrrolidin-1-yl-ethyl) -urea

Chemical Information

Sgc707

structure in first source

CAS Number1687736-54-4
PubChem CID90642938
IUPAC Name1-isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea
Molecular FormulaC16H18N4O2
Molecular Weight298.34
XLogP1.1
Topological Polar Surface Area74.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count22
Formal Charge0
Complexity409
SMILES
C1CCN(C1)C(=O)CNC(=O)NC2=CC3=C(C=C2)C=NC=C3
InChI
InChI=1S/C16H18N4O2/c21-15(20-7-1-2-8-20)11-18-16(22)19-14-4-3-13-10-17-6-5-12(13)9-14/h3-6,9-10H,1-2,7-8,11H2,(H2,18,19,22)
InChIKey
DMIDPTCQPIJYFE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Sgc707
CAS: 1687736-54-4
CID: 90642938
Formula: C16H18N4O2
MW: 298.34
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight298.34
XLogP31.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass298.14297583
Monoisotopic Mass298.14297583
Topological Polar Surface Area74.3 Ų
Heavy Atom Count22
Formal Charge0
Complexity409
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS131323SGC-707
5367/10SGC 707
A15450-500SGC 707 500mg
A15450-100SGC 707 100mg
A15450-10SGC 707 10mg
A15450-50SGC 707 50mg
A15450-25SGC 707 25mg
A15450-5SGC 707 5mg
TBI1610-25MGSGC-707, PRMT3 inhibitor
A15450-10mM-DSGC 707 10mM * 1mL in DMSO

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