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Abemaciclib

CAT: 0013-GTR19171447-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171447-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Abemaciclib methanesulfonate (LY2835219) is a potent and selective inhibitor of CDK4 (IC50=2 nM) and CDK6 (IC50=10 nM) . It is widely used in cancer research, demonstrating activity in both in vitro cell proliferation assays and in vivo xenograft models for studying cell cycle progression and oncology therapeutics.
CAS Number
1231930-82-7
Product Name Alternative
LY2835219 mesylate
Field of Research
Cell Biology
Purity
>98%
Bioactivity
CDK 4/6 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml)
Smiles
CS (O) (=O) =O.CCN1CCN (Cc2ccc (Nc3ncc (F) c (n3) -c3cc (F) c4nc (C) n (C (C) C) c4c3) nc2) CC1
Molecular Formula
C27H32F2N8·CH3SO3H
Molecular Weight
602.70
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[5-[ (4-Ethylpiperazin-1-yl) methyl]pyridine-2-yl]-5-fluoro-4- (7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl) pyrimidin-2-amine methanesulfonic acid salt

Alternative Products

CatalogName
FE103812-01Abemaciclib
C12488-5mgAbemaciclib mesylate
CS-O-32773Abemaciclib-d10
CS-O-32772Abemaciclib-d7
HY-W728130-01Abemaciclib-d5

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