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HMN-176

CAT: 0013-GTR19171052-04Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19171052-04Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HMN-176 is a stilbene-based small molecule that acts as a mitotic inhibitor by targeting polo-like kinase 1 (Plk1) . It is utilized in cancer research to study cell cycle disruption and has been investigated in both in vitro and in vivo experimental models for its antitumor potential.
CAS Number
173529-10-7
Product Name Alternative
HMN 176, HMN176, HMN-176, Inhibitor, inhibit, PLK, plk1, Polo-like Kinase (PLK)
Field of Research
Cell Biology
Purity
97.95% (May vary between batches)
Solubility
2% DMSO+40% PEG300+5% Tween 80+53% Saline:2 mg/mL (5.23 mM) ; DMSO:100 mg/mL (261.49 mM)
Smiles
COc1ccc (cc1) S (=O) (=O) Nc1ccccc1\C=C\c1cc[n+] ([O-]) cc1
Molecular Formula
C20H18N2O4S
Molecular Weight
382.43
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(E)-4-(2-((4-methoxyphenyl)sulfonamido)styryl)pyridine 1-oxide
CAS Number173529-10-7
PubChem CID54025051
IUPAC NameN-[6-[2-(1-hydroxy-4-pyridinylidene)ethylidene]cyclohexa-2,4-dien-1-ylidene]-4-methoxybenzenesulfonamide
Molecular FormulaC20H18N2O4S
Molecular Weight382.4
XLogP3.4
Topological Polar Surface Area87.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count27
Formal Charge0
Complexity846
SMILES
COC1=CC=C(C=C1)S(=O)(=O)N=C2C=CC=CC2=CC=C3C=CN(C=C3)O
InChI
InChI=1S/C20H18N2O4S/c1-26-18-8-10-19(11-9-18)27(24,25)21-20-5-3-2-4-17(20)7-6-16-12-14-22(23)15-13-16/h2-15,23H,1H3
InChIKey
MYEJOKLXXLVMPR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (E)-4-(2-((4-methoxyphenyl)sulfonamido)styryl)pyridine 1-oxide
CAS: 173529-10-7
CID: 54025051
Formula: C20H18N2O4S
MW: 382.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight382.4
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass382.09872823
Monoisotopic Mass382.09872823
Topological Polar Surface Area87.6 Ų
Heavy Atom Count27
Formal Charge0
Complexity846
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count2
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BA4420-5.1HMN-176
A16327-500HMN-176 500mg
A16327-10HMN-176 10mg
A16327-1HMN-176 1mg
A16327-25HMN-176 25mg
A16327-5HMN-176 5mg
A16327-100HMN-176 100mg
A16327-50HMN-176 50mg
A16327-2HMN-176 2mg

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