Products for Research Use Only
RegisterLogin

COR659

CAT: 0013-GTR19171042-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19171042-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
COR659 is a 2-acylaminothiophene derivative that functions as a GABAB receptor positive allosteric modulator and a cannabinoid CB1 receptor antagonist/inverse agonist. It has been shown to reduce alcohol and chocolate self-administration in rodent models, supporting its use in preclinical research on addiction and reward-related behaviors.
CAS Number
544450-68-2
Product Name Alternative
COR659, COR-659, COR 659, chocolate, CB1, Cannabinoid Receptor, CannabinoidReceptor, alcohol, GABA Receptor, GABAReceptor, GABAB, Gamma-aminobutyric acid Receptor, Inhibitor, inhibit, sucrose, γ-Aminobutyric acid Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.56% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.92 mM) ; DMSO:33.33 mg/mL (98.66 mM)
Smiles
CCc1c (C) sc (NC (=O) c2ccc (Cl) cc2) c1C (=O) OC
Molecular Formula
C16H16ClNO3S
Molecular Weight
337.82
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Methyl 2-(4-chlorobenzamido)-4-ethyl-5-methylthiophene-3-carboxylate
CAS Number544450-68-2
PubChem CID897320
IUPAC Namemethyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate
Molecular FormulaC16H16ClNO3S
Molecular Weight337.8
XLogP5
Topological Polar Surface Area83.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Heavy Atom Count22
Formal Charge0
Complexity412
SMILES
CCC1=C(SC(=C1C(=O)OC)NC(=O)C2=CC=C(C=C2)Cl)C
InChI
InChI=1S/C16H16ClNO3S/c1-4-12-9(2)22-15(13(12)16(20)21-3)18-14(19)10-5-7-11(17)8-6-10/h5-8H,4H2,1-3H3,(H,18,19)
InChIKey
AAFLALGGEYRGTR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Methyl 2-(4-chlorobenzamido)-4-ethyl-5-methylthiophene-3-carboxylate
CAS: 544450-68-2
CID: 897320
Formula: C16H16ClNO3S
MW: 337.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight337.8
XLogP35
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass337.0539422
Monoisotopic Mass337.0539422
Topological Polar Surface Area83.6 Ų
Heavy Atom Count22
Formal Charge0
Complexity412
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19200448-01COR627
GTR19200447-01COR628
GTR17950258COR15A Antibody
GTR17949834COR15B Antibody
GTR19082227-01Recombinant Chicken Olfactory receptor-like protein COR6 (COR6)
GTR19082223-01Recombinant Chicken Olfactory receptor-like protein COR5 (COR5)

Alternative Products

CatalogName
A8996-10COR659

Popular Products