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BP-1-102

CAT: 0013-GTR19170952-02Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170952-02Size:2 mg
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Description
BP-1-102 is a potent and selective oral STAT3 inhibitor that disrupts STAT3 activation by binding with high affinity (Kd: 504 nM) . It effectively suppresses the growth, survival, and invasion of STAT3-dependent cancer cells in vitro by downregulating key oncogenic targets like c-Myc and VEGF, and has demonstrated antitumor efficacy in vivo models.
CAS Number
1334493-07-0
Product Name Alternative
BP 1 102, BP1102, BP-1-102, Inhibitor, inhibit, STAT, STAT3
Field of Research
Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.61% (May vary between batches)
Solubility
DMSO:93 mg/mL (148.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.27 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN (CC (=O) N (Cc1ccc (cc1) C1CCCCC1) c1ccc (C (O) =O) c (O) c1) S (=O) (=O) c1c (F) c (F) c (F) c (F) c1F
Molecular Formula
C29H27F5N2O6S
Molecular Weight
626.59
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

BP-1-102

a STAT3 inhibitor; structure in first source

CAS Number1334493-07-0
PubChem CID53388144
IUPAC Name4-[(4-cyclohexylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid
Molecular FormulaC29H27F5N2O6S
Molecular Weight626.6
XLogP6.4
Topological Polar Surface Area124
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count12
Rotatable Bond Count9
Heavy Atom Count43
Formal Charge0
Complexity1050
SMILES
CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC(=C(C=C3)C(=O)O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F
InChI
InChI=1S/C29H27F5N2O6S/c1-35(43(41,42)28-26(33)24(31)23(30)25(32)27(28)34)15-22(38)36(19-11-12-20(29(39)40)21(37)13-19)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h7-13,17,37H,2-6,14-15H2,1H3,(H,39,40)
InChIKey
WNVSFFVDMUSXSX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of BP-1-102
CAS: 1334493-07-0
CID: 53388144
Formula: C29H27F5N2O6S
MW: 626.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight626.6
XLogP36.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count12
Rotatable Bond Count9
Exact Mass626.15099857
Monoisotopic Mass626.15099857
Topological Polar Surface Area124 Ų
Heavy Atom Count43
Formal Charge0
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
T3708-01BP-1-102
JDC49307-01BP 1-102
A20347-1BP-1-102 1mg
HY-100493RBP-1-102 (Standard)
A20347-100BP-1-102 100mg
A20347-50BP-1-102 50mg
A20347-25BP-1-102 25mg
A20347-10BP-1-102 10mg
A20347-5BP-1-102 5mg

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