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Rolapitant hydrochloride

CAT: 0013-GTR19170930-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170930-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rolapitant hydrochloride (CAS 858102-79-1) is a potent, selective, orally active NK1 receptor antagonist (Ki=0.66 nM) with long duration and no CYP3A4 interaction. It demonstrates central anti-emetic effects in ferret models, supporting research in chemotherapy-induced nausea and vomiting within neuropharmacology and oncology.
CAS Number
858102-79-1
Product Name Alternative
NK1, Neurokininreceptor, Neurokinin receptor, Rolapitant HCl, Rolapitant hydrochloride, Rolapitant Hydrochloride
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.35% (May vary between batches)
Solubility
DMSO:50 mg/mL (93.12 mM)
Smiles
Cl.C[C@@H] (OC[C@]1 (CC[C@]2 (CCC (=O) N2) CN1) c1ccccc1) c1cc (cc (c1) C (F) (F) F) C (F) (F) F
Molecular Formula
C25H27ClF6N2O2
Molecular Weight
536.94
Storage Conditions
-20°C
Notes
For research use only.

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