DAPI (dihydrochloride) (solution)

• UNSPSC Description:

  DAPI dihydrochloride (4',6-Diamidino-2-phenylindole dihydrochloride) (solution) is a DAPI dye. DAPI is a fluorescent dye that can bind strongly to DNA. DAPI binds to the A/T base pairs in the minor groove of double-stranded DNA (1 DAPI molecule can occupy 3 base pairs), which amplifies the fluorescence intensity by about 20 times. By observing the fluorescence intensity, DNA can be quantified. DAPI can also penetrate intact cell membranes and is often used to stain living and fixed cells[1].

• Target Antigen:

  DNA Stain

• Type:

  Dye Reagents

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dapi-dihydrochloride-solution.html

• Smiles:

  N=C(C1=CC2=C(C=C1)C=C(C3=CC=C(C(N)=N)C=C3)N2)N.[H]Cl.[H]Cl

• Molecular Weight:

  350.25

• References & Citations:

  [1]Kapuscinski J. DAPI: a DNA-specific fluorescent probe[J]. Biotechnic & histochemistry, 1995, 70(5): 220-233.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  28718-90-3