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Br-DAPI

CAT: 0804-HY-D1396-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D1396-01Size:5 mg
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Description
Br-DAPI is a marker dye in DAPI series. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells[1]. Storage: Keep away from light.
CAS Number
2387906-44-5
UNSPSC
12171500
Target
DNA Stain; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/br-dapi.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N=C(C1=CC2=C(C=C1)C(Br)=C(C3=CC=C(C(N)=N)C=C3)N2)N
Molecular Formula
C16H14BrN5
Molecular Weight
356.22
References & Citations
[1]Kapuscinski J, et al. DAPI: a DNA-specific fluorescent probe. Biotech Histochem. 1995 Sep;70 (5) :220-33.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Chemical Information

Br-DAPI
CAS Number2387906-44-5
PubChem CID162642091
IUPAC Name3-bromo-2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide
Molecular FormulaC16H14BrN5
Molecular Weight356.22
XLogP2.3
Topological Polar Surface Area116
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count22
Formal Charge0
Complexity446
SMILES
C1=CC(=CC=C1C2=C(C3=C(N2)C=C(C=C3)C(=N)N)Br)C(=N)N
InChI
InChI=1S/C16H14BrN5/c17-13-11-6-5-10(16(20)21)7-12(11)22-14(13)8-1-3-9(4-2-8)15(18)19/h1-7,22H,(H3,18,19)(H3,20,21)
InChIKey
GSBXNZFEZFIMCS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Br-DAPI
CAS: 2387906-44-5
CID: 162642091
Formula: C16H14BrN5
MW: 356.22
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight356.22
XLogP32.3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass355.04326
Monoisotopic Mass355.04326
Topological Polar Surface Area116 Ų
Heavy Atom Count22
Formal Charge0
Complexity446
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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