Products for Research Use Only

Fraxin

CAT: 0013-GTR19170837-09Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170837-09Size:200 mg
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Description
Fraxin, also known as Fraxoside, is the glucoside derivative of fraxetin. This small molecule is utilized in biochemical research, particularly in studies investigating its antioxidant and anti-inflammatory properties in various in vitro models.
CAS Number
524-30-1
Product Name Alternative
Inhibit, Inhibitor, Paviin, Fraxetin-8-O-glucoside, Fraxin, Fraxoside, GLUT9, Phosphodiesterase (PDE), phosphodiesterase, URAT1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.06% (May vary between batches)
Solubility
DMSO:50 mg/mL (135.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.4 mM)
Smiles
COc1cc2ccc (=O) oc2c (O[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]2O) c1O
Molecular Formula
C16H18O10
Molecular Weight
370.31
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Fraxin

Fraxin is a beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo. It has a role as a hepatoprotective agent, an anti-inflammatory agent and a plant metabolite. It is a beta-D-glucoside, an aromatic ether and a hydroxycoumarin. It is functionally related to a fraxetin.

CAS Number524-30-1
PubChem CID5273568
IUPAC Name7-hydroxy-6-methoxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
Molecular FormulaC16H18O10
Molecular Weight370.31
XLogP-0.6
Topological Polar Surface Area155
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count4
Heavy Atom Count26
Formal Charge0
Complexity539
SMILES
COC1=C(C(=C2C(=C1)C=CC(=O)O2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O
InChI
InChI=1S/C16H18O10/c1-23-7-4-6-2-3-9(18)25-14(6)15(11(7)20)26-16-13(22)12(21)10(19)8(5-17)24-16/h2-4,8,10,12-13,16-17,19-22H,5H2,1H3/t8-,10-,12+,13-,16+/m1/s1
InChIKey
CRSFLLTWRCYNNX-QBNNUVSCSA-N
Chemical Structure
2D Structure
2D structure of Fraxin
CAS: 524-30-1
CID: 5273568
Formula: C16H18O10
MW: 370.31
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight370.31
XLogP3-0.6
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count4
Exact Mass370.08999677
Monoisotopic Mass370.08999677
Topological Polar Surface Area155 Ų
Heavy Atom Count26
Formal Charge0
Complexity539
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes