Products for Research Use Only

AR7

CAT: 0013-GTR19170600-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170600-01Size:5 mg
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Description
AR7 is a selective antagonist of the retinoic acid receptor alpha (RARα) . It is a valuable research tool for investigating RARα signaling pathways in both cellular (in vitro) and animal (in vivo) models, particularly in studies of development, differentiation, and oncology.
CAS Number
80306-38-3
Product Name Alternative
AR7, AR-7, AR 7, acid, CMA, Inhibitor, inhibit, macroautophagy, RAR/RXR, RARα, receptor, Retinoic acid receptors, retinoic, RetinoidReceptor, Retinoid Receptor, Retinoid X receptors
Field of Research
Cell Biology, Neuroscience
Purity
>98%
Bioactivity
Activates chaperone mediated autophagy
Form
Powder
Solubility
Soluble in DMSO (30 mg/ml)
Smiles
Cc1ccc (cc1) C1=Nc2ccc (Cl) cc2OC1
Molecular Formula
C15H12ClNO
Molecular Weight
257.7
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
7-Chloro-3- (4-methylphenyl) -2H-1,4-benzoxazine

Chemical Information

7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine
CAS Number80306-38-3
PubChem CID44250175
IUPAC Name7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine
Molecular FormulaC15H12ClNO
Molecular Weight257.71
XLogP4.1
Topological Polar Surface Area21.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count18
Formal Charge0
Complexity322
SMILES
CC1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)OC2
InChI
InChI=1S/C15H12ClNO/c1-10-2-4-11(5-3-10)14-9-18-15-8-12(16)6-7-13(15)17-14/h2-8H,9H2,1H3
InChIKey
MVOZLTFXYGHZPM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine
CAS: 80306-38-3
CID: 44250175
Formula: C15H12ClNO
MW: 257.71
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight257.71
XLogP34.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass257.0607417
Monoisotopic Mass257.0607417
Topological Polar Surface Area21.6 Ų
Heavy Atom Count18
Formal Charge0
Complexity322
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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