Products for Research Use Only
RegisterLogin

(E/Z) -BCI

CAT: 0013-GTR19176762-06Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19176762-06Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(E/E) -BCI (NSC-150117) is a DUSP6 inhibitor with anti-inflammatory activity. It suppresses LPS-induced inflammation and oxidative stress in macrophages by inhibiting the NF-κB pathway and activating Nrf2 signaling. This compound is a useful research tool for studying inflammation, redox biology, and macrophage function in vitro.
CAS Number
15982-84-0
Product Name Alternative
Anti-inflammatory, Apoptosis, (E/Z) BCI, (E/Z) BCI, (E/Z) -BCI, DUSP6, ERK, death, gastric cancer, Inhibitor, inhibit, LPS, NSC150117, NSC-150117, NSC 150117, Nrf2, NF-κB, ROS, Phosphatase
Field of Research
Cell Biology, Metabolism Research
Purity
98.55% (May vary between batches)
Solubility
Ethanol:20 mg/mL (63.01 mM) ; DMSO:50 mg/mL (157.52 mM)
Smiles
O=C1C (=Cc2ccccc2) C (NC2CCCCC2) c2ccccc12
Molecular Formula
C22H23NO
Molecular Weight
317.42
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(E/Z)-Bci
CAS Number15982-84-0
PubChem CID5475586
IUPAC Name(2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one
Molecular FormulaC22H23NO
Molecular Weight317.4
XLogP4.7
Topological Polar Surface Area29.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count24
Formal Charge0
Complexity470
SMILES
C1CCC(CC1)NC\2C3=CC=CC=C3C(=O)/C2=C\C4=CC=CC=C4
InChI
InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1,3-4,7-10,13-15,17,21,23H,2,5-6,11-12H2/b20-15-
InChIKey
XJDKPLZUXCIMIS-HKWRFOASSA-N
Chemical Structure
2D Structure
2D structure of (E/Z)-Bci
CAS: 15982-84-0
CID: 5475586
Formula: C22H23NO
MW: 317.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight317.4
XLogP34.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass317.177964357
Monoisotopic Mass317.177964357
Topological Polar Surface Area29.1 Ų
Heavy Atom Count24
Formal Charge0
Complexity470
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19156974-01BCI
GTR19178468-01BCI
GTR19233936-01BcI-2/BcI-xI ligand 1
GTR19174970-01BCI-137
GTR19167711-01BCI-215
GTR19162218-01BCI-121
GTR19168544-01BCI-121
GTR19157311-01BCI-215
GTR19206476-01BCI hydrochloride
GTR19234015-01PROTAC BcI-2/BcI-xI Degrader-1

Alternative Products

CatalogName
M26187-01(E/Z) -BCI
MBS5766559(E/Z)-BCI
A22405-200(E/Z) -BCI 200mg
A22405-100(E/Z) -BCI 100mg
A22405-50(E/Z) -BCI 50mg
A22405-5(E/Z) -BCI 5mg
A22405-25(E/Z) -BCI 25mg
A22405-10(E/Z) -BCI 10mg
A22405-1(E/Z) -BCI 1mg
A22405-10mM-D(E/Z) -BCI 10mM * 1mL in DMSO

Popular Products