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Doxapram hydrochloride hydrate

CAT: 0013-GTR19176528-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19176528-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Doxapram hydrochloride hydrate is a potent inhibitor of TASK channel subtypes, with EC50 values of 410 nM for TASK-1, 9 μM for TASK-1/TASK-3 heterodimers, and 37 μM for TASK-3. This small molecule is a valuable research tool for studying the role of TASK channels in respiratory control, neuronal excitability, and cellular physiology in both in vitro and in vivo models.
CAS Number
7081-53-0
Product Name Alternative
Doxapram HCl, Doxapram hydrochloride, Doxapram Hydrochloride, Doxapram hydrochloride hydrate, Doxapram hydrochloride Hydrate, Doxapram hydrochloride monohydrate, Doxapram hydrochloride Monohydrate, Inhibitor, KcsA, inhibit, PotassiumChannel, Potassium Channel, TASK-1, TASK-1/TASK-3 heterodimeric, TASK-3
Field of Research
Pharmacology & Drug Discovery
Purity
99.64% (May vary between batches)
Solubility
Ethanol:2 mg/mL (4.62 mM) ; H2O:23 mg/mL (53.12 mM) ; DMSO:81 mg/mL (187.07 mM)
Smiles
Cl.CCN1CC (CCN2CCOCC2) C (C1=O) (c1ccccc1) c1ccccc1
Molecular Formula
C24H33ClN2O3 (C24H30N2O2·ClH·H2O)
Molecular Weight
432.99
Storage Conditions
-20°C
Notes
For research use only.

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