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Naftopidil

CAT: 0013-GTR19176083-03Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19176083-03Size:1 g
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Description
Naftopidil (Flivas, KT-611) is a selective α1-adrenergic receptor antagonist used as an antihypertensive agent. It is employed in pharmacological research to study receptor function and has been utilized in both in vitro binding assays and in vivo models of hypertension and benign prostatic hyperplasia.
CAS Number
57149-07-2
Product Name Alternative
Naftopidil, inhibit, KT611, KT-611, KT 611, Inhibitor, hyperplasia, Beta Receptor, BM 15275, BM15275, BM-15275, canine, Adrenergic Receptor, AdrenergicReceptor, prostatic, prostate, pressure, α1A-adrenergic receptor, α1D-adrenergic receptor, α1B-adrenergic receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.40% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.1 mM) ; DMSO:75 mg/mL (191.09 mM)
Smiles
O (CC (CN1CCN (CC1) C2=C (OC) C=CC=C2) O) C=3C4=C (C=CC3) C=CC=C4
Molecular Formula
C24H28N2O3
Molecular Weight
392.49
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Naftopidil

Naftopidil is a member of piperazines.

CAS Number57149-07-2
PubChem CID4418
IUPAC Name1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol
Molecular FormulaC24H28N2O3
Molecular Weight392.5
XLogP4.1
Topological Polar Surface Area45.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Heavy Atom Count29
Formal Charge0
Complexity483
SMILES
COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O
InChI
InChI=1S/C24H28N2O3/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23/h2-12,20,27H,13-18H2,1H3
InChIKey
HRRBJVNMSRJFHQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Naftopidil
CAS: 57149-07-2
CID: 4418
Formula: C24H28N2O3
MW: 392.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight392.5
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass392.20999276
Monoisotopic Mass392.20999276
Topological Polar Surface Area45.2 Ų
Heavy Atom Count29
Formal Charge0
Complexity483
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B1362-SNaftopidil

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