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RKI1313

CAT: 0013-GTR19173466-03Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173466-03Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RKI1313 is a selective ROCK inhibitor that blocks ROCK-dependent signaling, leading to inhibition of cytoskeletal reorganization, colony formation, migration, and invasion. It is a valuable research tool for studying Rho/ROCK pathways in cancer cell biology, fibrosis, and neurological disorders in both in vitro and in vivo models.
CAS Number
1342276-76-9
Product Name Alternative
Anticancer, migration, inhibit, Inhibitor, Rho-kinase, Rho-associated kinase, RKI 1313, RKI1313, RKI-1313, ROK, ROCK, ROCK2, ROCK1, ROCK substrates, Rho-associated protein kinase
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
≥95% (May vary between batches)
Solubility
DMSO:55 mg/mL (161.57 mM)
Smiles
N (C (NCC1=CC (OC) =CC=C1) =O) C2=NC (=CS2) C=3C=CN=CC3
Molecular Formula
C17H16N4O2S
Molecular Weight
340.4
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea
CAS Number1342276-76-9
PubChem CID53492330
IUPAC Name1-[(3-methoxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea
Molecular FormulaC17H16N4O2S
Molecular Weight340.4
XLogP2.3
Topological Polar Surface Area104
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count24
Formal Charge0
Complexity406
SMILES
COC1=CC=CC(=C1)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3
InChI
InChI=1S/C17H16N4O2S/c1-23-14-4-2-3-12(9-14)10-19-16(22)21-17-20-15(11-24-17)13-5-7-18-8-6-13/h2-9,11H,10H2,1H3,(H2,19,20,21,22)
InChIKey
BDCUKYUIVYKXCQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea
CAS: 1342276-76-9
CID: 53492330
Formula: C17H16N4O2S
MW: 340.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight340.4
XLogP32.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass340.09939694
Monoisotopic Mass340.09939694
Topological Polar Surface Area104 Ų
Heavy Atom Count24
Formal Charge0
Complexity406
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T2011-01RKI1313

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