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Compound 401

CAT: 0013-GTR19172109-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172109-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a potent and selective small molecule inhibitor of DNA-PK with an IC50 of 0.28 μM, which additionally inhibits mTOR while sparing PI3K. It is a valuable chemical probe for studying DNA damage response and repair pathways in both cellular and animal models of cancer research.
CAS Number
168425-64-7
Product Name Alternative
Inhibitor, inhibit, 2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one, DNA-dependent protein kinase, DNA-PK, DNAPK, Compound401, Compound-401, Compound 401
Field of Research
Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.19% (May vary between batches)
Solubility
DMSO:5.45 mg/mL (19.37 mM)
Smiles
O=c1cc (nc2c3ccccc3ccn12) N1CCOCC1
Molecular Formula
C16H15N3O2
Molecular Weight
281.31
Storage Conditions
-20°C
Notes
For research use only.

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