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TTBK1-IN-2

CAT: 0013-GTR19171850-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171850-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TTBK1-IN-2 is a potent small molecule inhibitor of Tau-Tubulin Kinase 1 (TTBK1), exhibiting IC50 values of 0.24 μM and 4.22 μM. It effectively reduces pathological TDP-43 phosphorylation in both cellular models and in vivo, as demonstrated in transgenic mouse spinal cords, making it a valuable research tool for neurodegenerative disease studies.
CAS Number
2765453-51-6
Product Name Alternative
N-[4- (4-chlorophenoxy) phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Microtubule Associated, MicrotubuleAssociated, tau, TTBK1-IN-2, Tubulin
Field of Research
Neuroscience, Signal Transduction
Purity
99.81% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.94 mM) ; DMSO:55 mg/mL (163.32 mM)
Smiles
Clc1ccc (Oc2ccc (Nc3ncnc4[nH]ccc34) cc2) cc1
Molecular Formula
C18H13ClN4O
Molecular Weight
336.77
Storage Conditions
-20°C
Notes
For research use only.

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