TA-02

CAT: 0013-GTR19170470-01Size: 500 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19170470-01Size:500 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

TA-02 is a potent and selective p38 MAPK inhibitor (IC50 = 20 nM) that also demonstrates activity against TGFBR-2. This small molecule is a valuable research tool for investigating inflammatory pathways, fibrosis, and cancer biology in both cellular and animal models.

CAS Number

1784751-19-4

Product Name Alternative

COX-2, DMPK2, CIT, CK1ε, Autophagy, BDNF, DDR1 CK1δ, LEF-1, MEK5, Inhibitor, inhibit, JNK2, JNK3, JNK1, p38 MAPK, p38MAPK, TA02, TA-02, TA 02, TCF

Field of Research

Cell Biology, Signal Transduction

Purity

99.35% (May vary between batches)

Solubility

DMSO:50 mg/mL (150 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6 mM)

Smiles

Fc1ccc (cc1) -c1nc ([nH]c1-c1ccncc1) -c1ccccc1F

Molecular Formula

C20H13F2N3

Molecular Weight

333.33

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

4-(2-(2-Fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridine

CAS Number	1784751-19-4
PubChem CID	91691130
IUPAC Name	4-[2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine
Molecular Formula	C20H13F2N3
Molecular Weight	333.3
XLogP	4.2
Topological Polar Surface Area	41.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	25
Formal Charge	0
Complexity	421

SMILES

C1=CC=C(C(=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)F

InChI

InChI=1S/C20H13F2N3/c21-15-7-5-13(6-8-15)18-19(14-9-11-23-12-10-14)25-20(24-18)16-3-1-2-4-17(16)22/h1-12H,(H,24,25)

InChIKey

QIFJOFNVIVQRNJ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1784751-19-4

CID: 91691130

Formula: C20H13F2N3

MW: 333.3

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	333.3
XLogP3	4.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	333.10775375
Monoisotopic Mass	333.10775375
Topological Polar Surface Area	41.6 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	421
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
BUP13271-01	TA-02
B4924-50	TA 02
A13644-100	TA-02 100mg
A13644-10	TA-02 10mg
A13644-5	TA-02 5mg
A13644-50	TA-02 50mg
HY-100115R	TA-02 (Standard)
A13644-25	TA-02 25mg
A13644-10mM-D	TA-02 10mM * 1mL in DMSO
HY-176913	TA

TA-02

Chemical Information

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