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MMAD

CAT: 0013-GTR19170444-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170444-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MMAD (Demethyldolastatin 10) is a potent tubulin-binding agent used as a cytotoxic payload in antibody-drug conjugates (ADCs) . Its mechanism of inhibiting microtubule assembly is applied in oncology research for evaluating ADC efficacy in both in vitro cytotoxicity assays and in vivo xenograft models.
CAS Number
203849-91-6
Product Name Alternative
Inhibitor, Monomethyl Dolastatin 10, Monomethyl Dolastatin10, Monomethyl Dolastatin-10, Monomethylauristatin D, Microtubule Associated, MicrotubuleAssociated, Microtubule/Tubulin, MMAD, inhibit, ADCCytotoxin, ADC Cytotoxin, ADC Payload, Demethyldolastatin 10, Demethyldolastatin10, Demethyldolastatin-10
Field of Research
Signal Transduction
Purity
99.25% (May vary between batches)
Solubility
DMSO:24.5 mg/mL (31.77 mM)
Smiles
[H][C@]1 (CCCN1C (=O) C[C@@H] (OC) [C@H] ([C@@H] (C) CC) N (C) C (=O) [C@@H] (NC (=O) [C@@H] (NC) C (C) C) C (C) C) [C@H] (OC) [C@@H] (C) C (=O) N[C@@H] (Cc1ccccc1) c1nccs1
Molecular Formula
C41H66N6O6S
Molecular Weight
771.06
Storage Conditions
-20°C
Notes
For research use only.

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