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SR-18292

CAT: 0013-GTR19170292-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170292-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR-18292 is a small molecule inhibitor that targets PGC-1α, promoting its acetylation to suppress hepatic gluconeogenesis. This mechanism reduces glucose output in hepatocytes, making it a useful research tool for studying metabolic disorders like type 2 diabetes in both cellular and animal models.
CAS Number
2095432-55-4
Product Name Alternative
Autophagy, Inhibitor, inhibit, SR 18292, SR18292, SR-18292, PGC-1α, PPARγ coactivator-1α
Field of Research
Cell Biology, Metabolism Research
Purity
99.00% (May vary between batches)
Solubility
H2O:Insoluble; Ethanol:10 mg/mL (27.29 mM) ; DMSO:245 mg/mL (668.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.46 mM)
Smiles
Cc1ccc (CN (CC (O) COc2cccc3[nH]ccc23) C (C) (C) C) cc1
Molecular Formula
C23H30N2O2
Molecular Weight
366.5
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-((1,1-dimethylethyl)((4-methylphenyl)methyl)amino)-3-(1H-indol-4-yloxy)-2-propanol
CAS Number2095432-55-4
PubChem CID129896798
IUPAC Name1-[tert-butyl-[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)propan-2-ol
Molecular FormulaC23H30N2O2
Molecular Weight366.5
XLogP4.3
Topological Polar Surface Area48.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count8
Heavy Atom Count27
Formal Charge0
Complexity442
SMILES
CC1=CC=C(C=C1)CN(CC(COC2=CC=CC3=C2C=CN3)O)C(C)(C)C
InChI
InChI=1S/C23H30N2O2/c1-17-8-10-18(11-9-17)14-25(23(2,3)4)15-19(26)16-27-22-7-5-6-21-20(22)12-13-24-21/h5-13,19,24,26H,14-16H2,1-4H3
InChIKey
BNRANURXPKRRKP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-((1,1-dimethylethyl)((4-methylphenyl)methyl)amino)-3-(1H-indol-4-yloxy)-2-propanol
CAS: 2095432-55-4
CID: 129896798
Formula: C23H30N2O2
MW: 366.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight366.5
XLogP34.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count8
Exact Mass366.230728204
Monoisotopic Mass366.230728204
Topological Polar Surface Area48.5 Ų
Heavy Atom Count27
Formal Charge0
Complexity442
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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