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Pyr41

CAT: 0013-GTR19169748-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169748-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PYR-41 is a cell-permeable small molecule that selectively inhibits the ubiquitin-activating enzyme E1 without affecting E2 enzymes. It is widely used in vitro and in vivo to study ubiquitination pathways in cancer research, neurodegenerative disease models, and cellular protein degradation mechanisms.
CAS Number
418805-02-4
Product Name Alternative
Apoptosis, E1 activating enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E2 conjugating enzyme, E2 Enzyme, E1Enzyme, E3Enzyme, E3 ligating enzyme, E2Enzyme, E3 Enzyme, Inhibitor, inhibit, PYR41, PYR-41, PYR 41, Ubiquitin activating enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin-activating Enzyme E1
Field of Research
Protein Biochemistry
Purity
>98%
Bioactivity
E1 UAE inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
CCOC (=O) c1ccc (cc1) N1NC (=O) \C (=C\c2ccc (o2) [N+] ([O-]) =O) C1=O
Molecular Formula
C17H13N3O7
Molecular Weight
371.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4-[4- (5-Nitro-furan-2-ylmethylene) -3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester

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