Products for Research Use Only

CH7057288

CAT: 0013-GTR19169565-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169565-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CH7057288 is a potent and selective pan-TRK inhibitor, demonstrating low nanomolar IC50 values against TRKA (1.1 nM), TRKB (7.8 nM), and TRKC (5.1 nM) . It is a valuable research tool for investigating TRK kinase biology in cellular assays and has shown utility in preclinical models of TRK-driven cancers.
CAS Number
2095616-82-1
Product Name Alternative
CH7057288, CH-7057288, CH 7057288, inhibit, Inhibitor, Tropomyosin related kinase receptor, Trkreceptor, Trk Receptor, Trk receptor, Trk
Field of Research
Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:34 mg/mL (59.68 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.51 mM)
Smiles
Cc1cc (cc (n1) C#Cc1ccc2c3c (oc2c1) C (C) (C) c1cc (NS (C) (=O) =O) ccc1C3=O) C (=O) NC (C) (C) C
Molecular Formula
C32H31N3O5S
Molecular Weight
569.67
Storage Conditions
-20°C
Notes
For research use only.