Products for Research Use Only
RegisterLogin

NG25

CAT: 0013-GTR19169556-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19169556-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NG25 is a potent and selective small molecule inhibitor targeting both TAK1 and MAP4K2, with respective IC50 values of 149 nM and 21.7 nM. This compound is a valuable research tool for investigating inflammatory and oncogenic signaling pathways in both cellular and animal models.
CAS Number
1315355-93-1
Product Name Alternative
MAP4K, MAP4K2/TAK1, MAP3K, MAPK Kinase Kinase Kinase, MAP kinase kinase kinase, MEKK, MAPKKK, Inhibitor, NG 25, NG25, NG-25, inhibit
Field of Research
Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (31.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.72 mM)
Smiles
CCN1CCN (Cc2ccc (NC (=O) c3ccc (C) c (Oc4ccnc5[nH]ccc45) c3) cc2C (F) (F) F) CC1
Molecular Formula
C29H30F3N5O2
Molecular Weight
537.58
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

NG-25
CAS Number1315355-93-1
PubChem CID53340664
IUPAC NameN-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
Molecular FormulaC29H30F3N5O2
Molecular Weight537.6
XLogP4.9
Topological Polar Surface Area73.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Heavy Atom Count39
Formal Charge0
Complexity808
SMILES
CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F
InChI
InChI=1S/C29H30F3N5O2/c1-3-36-12-14-37(15-13-36)18-21-6-7-22(17-24(21)29(30,31)32)35-28(38)20-5-4-19(2)26(16-20)39-25-9-11-34-27-23(25)8-10-33-27/h4-11,16-17H,3,12-15,18H2,1-2H3,(H,33,34)(H,35,38)
InChIKey
SMPGEBOIKULBCT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of NG-25
CAS: 1315355-93-1
CID: 53340664
Formula: C29H30F3N5O2
MW: 537.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight537.6
XLogP34.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass537.23515970
Monoisotopic Mass537.23515970
Topological Polar Surface Area73.5 Ų
Heavy Atom Count39
Formal Charge0
Complexity808
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR18156555NG2 Antibody
GTR18895622NG2 peptide
GTR17970021Ng2 Antibody
GTR18075587-01NG2 Antibody
GTR18169826NG2 Antibody
GTR17856360NG2 Antibody
GTR18574817CSPG4 Antibody / NG2
GTR19144724-01NG2 binding peptide
GTR18793052CSPG4/NG2 Antibody
GTR18082659-01CSPG4 Antibody / NG2

Alternative Products

CatalogName
A3658-10NG25
A15185-100NG25 100mg
HY-15434ANG25 (trihydrochloride)
MBS5812442NG25 trihydrochloride
A15185-5NG25 5mg
A15185-500NG25 500mg
A15185-50NG25 50mg
A15185-10NG25 10mg
HY-15434RNG25 (Standard)

Popular Products