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IWP-4

CAT: 0013-GTR19169007-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169007-02Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IWP-4 is a potent small molecule inhibitor of Wnt protein production. It is widely used in research to investigate Wnt signaling pathways in both cellular (in vitro) and animal (in vivo) models of development, stem cell biology, and cancer.
CAS Number
686772-17-8
Product Name Alternative
Inhibitor, Inhibitor of Wnt Production-4, IWP4, IWP-4, IWP 4, inhibit, beta-catenin, betacatenin, bcatenin, Wnt/β-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, βcatenin
Field of Research
Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Wnt inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 5 mg/ml)
Smiles
COc1ccccc1-n1c (SCC (=O) Nc2nc3ccc (C) cc3s2) nc2CCSc2c1=O
Molecular Formula
C23H20N4O3S3
Molecular Weight
496.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (6-Methyl-2-benzothiazolyl) -2-[[3,4,6,7-tetrahydro-3- (2-methoxyphenyl) -4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-acetamide

Chemical Information

2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
CAS Number686772-17-8
PubChem CID2155264
IUPAC Name2-[[3-(2-methoxyphenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
Molecular FormulaC23H20N4O3S3
Molecular Weight496.6
XLogP4.8
Topological Polar Surface Area163
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Heavy Atom Count33
Formal Charge0
Complexity851
SMILES
CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5OC)SCC4
InChI
InChI=1S/C23H20N4O3S3/c1-13-7-8-14-18(11-13)33-22(24-14)26-19(28)12-32-23-25-15-9-10-31-20(15)21(29)27(23)16-5-3-4-6-17(16)30-2/h3-8,11H,9-10,12H2,1-2H3,(H,24,26,28)
InChIKey
RHUJMHOIQBDFQR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
CAS: 686772-17-8
CID: 2155264
Formula: C23H20N4O3S3
MW: 496.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight496.6
XLogP34.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass496.06975403
Monoisotopic Mass496.06975403
Topological Polar Surface Area163 Ų
Heavy Atom Count33
Formal Charge0
Complexity851
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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