RegisterLogin

IWP-4

CAT: 0026-2650-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-2650-5Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IWP-4 is a potent inhibitor of Wnt production that blocks Wnt pathway activity in vitro (IC₅₀ = 25 nM). IWP-4 inactivates Porcupine (porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. At 5 μM, IWP-4 has been shown to block Wnt-dependent phosphorylation of the low-density lipoprotein receptor-related protein 6 receptor and the scaffold protein Dishevelled, preventing the accumulation of β-catenin. IWP-4 has been used to induce cardiomyocyte differentiation from human pluripotent stem cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

Related Products

CatalogName
2349-5IWP-3
1962-25IWP-2
2349-1IWP-3
1962-5IWP-2
E4645-1004-Hydroxynonenal (4-HNE) ELISA Kit
B3134-104-Aminonaphthalimide
B1630-5WIKI-4
B2495-254μ8C
B2330-25PFI-4
B1921-10004'-Hydroxychalcone

Alternative Products

CatalogName
MBS3841979-01IWP-4
M17568-01IWP 4
A17004-10IWP-4 10mg
A17004-50IWP-4 50mg
A17004-100IWP-4 100mg
A17004-1IWP-4 1mg
A17004-5IWP-4 5mg
A17004-25IWP-4 25mg
TBI3370-25MGIWP-4, Wnt inhibitor

Popular Products