Products for Research Use Only
RegisterLogin

YS-370

CAT: 0013-GTR19168798-06Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19168798-06Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
YS-370 is an orally bioavailable small molecule that inhibits P-glycoprotein (P-gp) and moderately inhibits CYP3A4. It reverses multidrug resistance to agents like paclitaxel and colchicine in vitro and demonstrates enhanced antitumor efficacy in combination with paclitaxel in vivo.
CAS Number
2470908-79-1
Product Name Alternative
YS370, YS-370, YS 370, P-gp, Pgp
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.50% (May vary between batches)
Solubility
DMSO:6 mg/mL (9.04 mM)
Smiles
COc1cc2ncnc (-c3c (-c4ccccc4) n (Cc4ccccc4Br) c4ccccc34) c2cc1OCCCN1CCOCC1
Molecular Formula
C37H35BrN4O3
Molecular Weight
663.6
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-[3-[4-[1-[(2-Bromophenyl)methyl]-2-phenylindol-3-yl]-7-methoxyquinazolin-6-yl]oxypropyl]morpholine
CAS Number2470908-79-1
PubChem CID162679251
IUPAC Name4-[3-[4-[1-[(2-bromophenyl)methyl]-2-phenylindol-3-yl]-7-methoxyquinazolin-6-yl]oxypropyl]morpholine
Molecular FormulaC37H35BrN4O3
Molecular Weight663.6
XLogP7.2
Topological Polar Surface Area61.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Heavy Atom Count45
Formal Charge0
Complexity903
SMILES
COC1=C(C=C2C(=C1)N=CN=C2C3=C(N(C4=CC=CC=C43)CC5=CC=CC=C5Br)C6=CC=CC=C6)OCCCN7CCOCC7
InChI
InChI=1S/C37H35BrN4O3/c1-43-33-23-31-29(22-34(33)45-19-9-16-41-17-20-44-21-18-41)36(40-25-39-31)35-28-13-6-8-15-32(28)42(24-27-12-5-7-14-30(27)38)37(35)26-10-3-2-4-11-26/h2-8,10-15,22-23,25H,9,16-21,24H2,1H3
InChIKey
WSOJDUFWINGDJI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-[3-[4-[1-[(2-Bromophenyl)methyl]-2-phenylindol-3-yl]-7-methoxyquinazolin-6-yl]oxypropyl]morpholine
CAS: 2470908-79-1
CID: 162679251
Formula: C37H35BrN4O3
MW: 663.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight663.6
XLogP37.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Exact Mass662.18925
Monoisotopic Mass662.18925
Topological Polar Surface Area61.6 Ų
Heavy Atom Count45
Formal Charge0
Complexity903
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19192239YS 3025
GTR19192236YS 3643
GTR19175615-01YS-49
GTR19192234YS 3646
GTR19192233YS 51
GTR19192232YS 822A
GTR19202910-01YS-201
GTR19202368-01YS-121
GTR19219164-01YS-363
GTR19192238YS 3621

Alternative Products

CatalogName
BA6844-50YS-370
C4930-5YS-121
BA6383-25YS-67
BA3181-50YS-363
BA6584-1YS-201
T35279YS 3646
MBS5784770YS 822A
MBS5784765YS 3621
MBS5784764YS 3025
BA5100-5.1YS-49

Popular Products