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GS-444217

CAT: 0013-GTR19168563-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168563-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GS-444217 is a potent and selective ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1), exhibiting an IC50 of 2.87 nM. This small molecule is a valuable research tool for investigating the role of ASK1 in cellular stress responses, inflammation, and fibrotic diseases in both in vitro and in vivo experimental models.
CAS Number
1262041-49-5
Product Name Alternative
Apoptosis, ASK1, MAP3K, MAP kinase kinase kinase, MEKK, MAPKKK, Inhibitor, GS 444217, GS444217, GS-444217, inhibit
Field of Research
Cell Biology, Signal Transduction
Purity
99.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.86 mM) ; DMSO:55 mg/mL (133.67 mM)
Smiles
O=C (Nc1cccc (c1) -c1nncn1C1CC1) c1cc (ccn1) -n1cnc (c1) C1CC1
Molecular Formula
C23H21N7O
Molecular Weight
411.46
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
MBS3844962-01GS-444217
A20517-100GS-444217 100mg
A20517-50GS-444217 50mg
A20517-25GS-444217 25mg
HY-100844RGS-444217 (Standard)
A20517-5GS-444217 5mg
A20517-10GS-444217 10mg
A20517-1GS-444217 1mg
A20517-10mM-DGS-444217 10mM * 1mL in DMSO
MBS131349Selonsertib (GS-4997; GS4997; GS 4997)

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