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Lomibuvir

CAT: 0013-GTR19168136-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168136-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lomibuvir (VCH-222) is a potent, non-nucleoside allosteric inhibitor of the Hepatitis C virus NS5B RNA-dependent RNA polymerase, exhibiting high affinity with a Kd of 17 nM. It demonstrates strong antiviral activity in HCV subgenomic replicon assays (EC50 = 5.2 nM) and preferentially blocks elongative RNA synthesis. This small molecule is a valuable tool for investigating HCV replication mechanisms in vitro.
CAS Number
1026785-55-6
Product Name Alternative
DNA/RNA Synthesis, cis-isomer, cis-Lomibuvir, Lomibuvir, inhibit, non-nucleoside polymerase, Inhibitor, HCV Protease, HCVProtease, HCV NS5B 1a, HCV NS5B 1b, HCV, Hepatitis C virus, VCH222, VCH-222, VCH 222, VX 222, VX222, VX-222, RdRp
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry
Purity
99.83% (May vary between batches)
Solubility
Ethanol:82 mg/mL (184.02 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:82 mg/mL (184.02 mM)
Smiles
CC1CCC (CC1) C (=O) N (C1CCC (O) CC1) c1cc (sc1C (O) =O) C#CC (C) (C) C
Molecular Formula
C25H35NO4S
Molecular Weight
445.61
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-75800-01Lomibuvir
HY-114571-01Cis-Lomibuvir
HY-75800R-01Lomibuvir (Standard)
C16340-50mgLomibuvir (VX-222)
A4032-5VX-222 (VCH-222, Lomibuvir)

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