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Lomibuvir

CAT: 0931-T6729-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6729-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1026785-55-6
Target
HCV Protease, DNA/RNA Synthesis
Related Pathways
Proteases/Proteasome, Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
>99.99%
Bioactivity
Lomibuvir (VCH-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo -initiated RNA synthesis [1].
Smiles
CC1CCC(CC1)C(=O)N(C1CCC(O)CC1)c1cc(sc1C(O)=O)C#CC(C)(C)C
Molecular Formula
C25H35NO4S
Molecular Weight
445.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-75800R-01Lomibuvir (Standard)
S1480-01Lomibuvir (VX-222)
A4032-5VX-222 (VCH-222, Lomibuvir)

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