Lomibuvir

• Target :

  HCV Protease|||DNA/RNA Synthesis

• Related Pathways :

  Proteases/Proteasome|||Microbiology/Virology|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Purity :

  >99.99%

• Bioactivity :

  Lomibuvir (VCH-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo -initiated RNA synthesis [1].

• Smiles :

  CC1CCC(CC1)C(=O)N(C1CCC(O)CC1)c1cc(sc1C(O)=O)C#CC(C)(C)C

• Molecular Formula :

  C25H35NO4S

• Molecular Weight :

  445.61

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1026785-55-6