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AI-10-49

CAT: 0013-GTR19168112-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168112-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AI-10-49 is a potent small molecule that selectively disrupts the interaction between the CBFβ-SMMHC oncoprotein and RUNX1, exhibiting an IC50 of 260 nM. This inhibitor is a valuable research tool for investigating acute myeloid leukemia (AML) pathogenesis and evaluating therapeutic strategies in cellular models.
CAS Number
1256094-72-0
Product Name Alternative
Inhibit, Inhibitor, AI1049, AI-10-49, AI 10 49, DNASynthesis, DNA Synthesis, CBFβ-SMMHC, RNASynthesis, RNA Synthesis
Field of Research
Cell Biology, Molecular Biology
Purity
97.14% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5 mM) ; DMSO:93 mg/mL (140.8 mM) ; Ethanol:93 mg/mL (140.8 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
FC (F) (F) Oc1ccc2nc ([nH]c2c1) -c1ccc (OCCOCCOc2ccc (nc2) -c2nc3ccc (OC (F) (F) F) cc3[nH]2) cn1
Molecular Formula
C30H22F6N6O5
Molecular Weight
660.52
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
A8694-5.1AI-10-49
A15521-100AI-10-49 100mg
A15521-25AI-10-49 25mg
A15521-200AI-10-49 200mg
A15521-10AI-10-49 10mg
A15521-50AI-10-49 50mg
A15521-5AI-10-49 5mg
A15521-2AI-10-49 2mg
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HY-138617-01AI-10-47

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