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AI-10-47

CAT: 0013-GTR19166928-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166928-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AI-10-47 is a potent small molecule inhibitor that disrupts the interaction between CBFβ and RUNX transcription factors, exhibiting an IC50 of 3.2 μM. This compound serves as a valuable chemical probe for researching RUNX-dependent pathways in cancer and hematopoiesis, applicable in both cellular and biochemical assays.
CAS Number
1256094-31-1
Product Name Alternative
AI 10 47, AI1047, AI-10-47, 1H-Benzimidazole, 2- (2-pyridinyl) -6- (trifluoromethoxy) -AI-10-47, CBFβ, CBFβ-RUNX binding, leukemia, ME-1, M0-91, RUNX, THP-1, TUR, U937
Purity
98.51% (May vary between batches)
Solubility
DMSO:100 mg/mL (358.14 mM)
Smiles
FC (F) (F) Oc1ccc2nc ([nH]c2c1) -c1ccccn1
Molecular Formula
C13H8F3N3O
Molecular Weight
279.22
Storage Conditions
-20°C
Notes
For research use only.

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