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EAI045

CAT: 0013-GTR19168048-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168048-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EAI045 is a selective allosteric inhibitor that potently targets drug-resistant EGFR mutants while sparing the wild-type receptor. It is a valuable chemical probe for studying resistance mechanisms in non-small cell lung cancer (NSCLC) and has demonstrated efficacy in both cellular assays and in vivo models.
CAS Number
1942114-09-1
Product Name Alternative
EAI 045, EAI045, EAI-045, HER1, EGFR, EGFR mutants, ErbB-1, Epidermal growth factor receptor, inhibit, Inhibitor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:16.67 mg/mL (43.48 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.22 mM)
Smiles
Oc1ccc (F) cc1C (N1Cc2ccccc2C1=O) C (=O) Nc1nccs1
Molecular Formula
C19H14FN3O3S
Molecular Weight
383.4
Storage Conditions
-20°C
Notes
For research use only.

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