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ICA-121431

CAT: 0013-GTR19167699-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167699-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ICA-121431 is a potent and selective small molecule inhibitor of the rat Nav1.7 voltage-gated sodium channel, exhibiting an IC50 of 19 nM. Its selectivity profile, showing minimal activity against human Nav1.5 and Nav1.7, makes it a valuable pharmacological tool for in vitro and in vivo pain research and channelopathy studies.
CAS Number
313254-51-2
Product Name Alternative
Channel, 2,2-Diphenyl-N-[4- (thiazol-2-ylsulfamoyl, ICA121431, ICA-121431, ICA 121431, inhibitor, Na+ channels, Na channels, Nav, Nav1.7 channel, inhibit, TTX-resistant, Sodium Channel, SodiumChannel
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Nav1.1/1.3 inhibitor (selective)
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
O=C (Nc1ccc (cc1) S (=O) (=O) Nc1nccs1) C (c1ccccc1) c1ccccc1
Molecular Formula
C23H19N3O3S2
Molecular Weight
449.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2,2-Diphenyl-N-[4- (1,3-thiazol-2-ylsulfamoyl) phenyl]acetamide

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B5802-5ICA 121431
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A13773-2ICA-121431 2mg
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