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Selitrectinib

CAT: 0013-GTR19167610-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167610-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selitrectinib (LOXO-195) is a highly potent and selective next-generation TRK inhibitor, targeting TrkA and TrkC with IC50 values of 0.6 and <2.5 nM, respectively. It is a valuable research tool for studying TRK-driven cancers, demonstrating activity in both cellular assays and in vivo models of acquired resistance to first-generation TRK inhibitors.
CAS Number
2097002-61-2
Product Name Alternative
Inhibitor, inhibit, LOXO195, LOXO-195, LOXO 195, Selitrectinib, Trk Receptor, Trkreceptor, Trk receptor, Trk, Tropomyosin related kinase receptor
Field of Research
Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM) ; DMSO:65 mg/mL (170.86 mM)
Smiles
[H][C@]12CCCN1c1ccn3ncc (C (=O) N[C@H] (C) CCc4ncc (F) cc24) c3n1
Molecular Formula
C20H21FN6O
Molecular Weight
380.42
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
MBS5758331Selitrectinib
A19252-100Selitrectinib 100mg
M28716-01(3aR) -Selitrectinib
HY-101977R-01Selitrectinib (Standard)
A19252-10Selitrectinib 10mg
A19252-1Selitrectinib 1mg
A19252-50Selitrectinib 50mg
A19252-25Selitrectinib 25mg
A19252-5Selitrectinib 5mg
S8636-10mM/1mLSelitrectinib (LOXO-195)

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